Publications



Consensus definition of sludge and microlithiasis as a possible cause of pancreatitis


Zorniak, M., Sirtl, S., Beyer, G., Mahajan, U. M., Bretthauer, K., Schirra, J., Schulz, C., Kohlmann, T., Lerch, M. M., Mayerle, J., and Team, L. M. E. S. (2023). Gut [Epub ahead of print]. doi: 10.1136/gutjnl-2022-327955

eIF3 mRNA selectivity profiling reveals eIF3k as a cancer-relevant regulator of ribosome content


Duan, H. R., Zhang, S. Q., Zarai, Y., Ollinger, R., Wu, Y. M., Sun, L., Hu, C., He, Y. H., Tian, G. Y., Rad, R., Kong, X. Q., Cheng, Y. B., Tuller, T., and Wolf, D. A. (2023). EMBO J [Epub ahead of print]. doi: 10.15252/embj.2022112362

Accurate prediction of histological grading of intraductal papillary mucinous neoplasia using deep learning


Schulz, D., Heilmaier, M., Phillip, V., Treiber, M., Mayr, U., Lahmer, T., Mueller, J., Demir, I. E., Friess, H., Reichert, M., Schmid, R. M., and Abdelhafez, M. (2023). Endoscopy 55, 415-422. doi: 10.1055/a-1971-1274

Single-cell profiling to explore pancreatic cancer heterogeneity, plasticity and response to therapy


Barthel, S., Falcomata, C., Rad, R., Theis, F. J., and Saur, D. (2023). Nat Cancer 4, 454-467. doi: 10.1038/s43018-023-00526-x

In vivo interrogation of regulatory genomes reveals extensive quasi-insufficiency in cancer evolution


Fischer, A., Lersch, R., de Andrade Kratzig, N., Strong, A., Friedrich, M. J., Weber, J., Engleitner, T., Ollinger, R., Yen, H. Y., Kohlhofer, U., Gonzalez-Menendez, I., Sailer, D., Kogan, L., Lahnalampi, M., Laukkanen, S., Kaltenbacher, T., Klement, C., Rezaei, M., Ammon, T., Montero, J. J., Schneider, G., Mayerle, J., Heikenwalder, M., Schmidt-Supprian, M., Quintanilla-Martinez, L., Steiger, K., Liu, P., Cadinanos, J., Vassiliou, G. S., Saur, D., Lohi, O., Heinaniemi, M., Conte, N., Bradley, A., Rad, L., and Rad, R. (2023). Cell Genom 3, 100276. doi: 10.1016/j.xgen.2023.100276

Long-term persistence and functionality of adoptively transferred antigen-specific T cells with genetically ablated PD-1 expression


Dotsch, S., Svec, M., Schober, K., Hammel, M., Wanisch, A., Gokmen, F., Jarosch, S., Warmuth, L., Barton, J., Cicin-Sain, L., D'Ippolito, E., and Busch, D. H. (2023). Proc Natl Acad Sci U S A 120, e2200626120. doi: 10.1073/pnas.2200626120

Non-canonical functions of SNAIL drive context-specific cancer progression


Paul, M. C., Schneeweis, C., Falcomata, C., Shan, C., Rossmeisl, D., Koutsouli, S., Klement, C., Zukowska, M., Widholz, S. A., Jesinghaus, M., Heuermann, K. K., Engleitner, T., Seidler, B., Sleiman, K., Steiger, K., Tschurtschenthaler, M., Walter, B., Weidemann, S. A., Pietsch, R., Schnieke, A., Schmid, R. M., Robles, M. S., Andrieux, G., Boerries, M., Rad, R., Schneider, G., and Saur, D. (2023). Nat Commun 14, 1201. doi: 10.1038/s41467-023-36505-0

Definition of age-dependent reference values for the diameter of the common bile duct and pancreatic duct on MRCP: a population-based, cross-sectional cohort study


Beyer, G., Kasprowicz, F., Hannemann, A., Aghdassi, A., Thamm, P., Volzke, H., Lerch, M. M., Kuhn, J. P., and Mayerle, J. (2023). Gut [Epub ahead of print]. doi: 10.1136/gutjnl-2021-326106

Adipocyte-derived extracellular vesicles increase insulin secretion through transport of insulinotropic protein cargo


Kulaj, K., Harger, A., Bauer, M., Caliskan, O. S., Gupta, T. K., Chiang, D. M., Milbank, E., Reber, J., Karlas, A., Kotzbeck, P., Sailer, D. N., Volta, F., Lutter, D., Prakash, S., Merl-Pham, J., Ntziachristos, V., Hauner, H., Pfaffl, M. W., Tschop, M. H., Muller, T. D., Hauck, S. M., Engel, B. D., Gerdes, J. M., Pfluger, P. T., Krahmer, N., and Stemmer, K. (2023). Nat Commun 14, 709. doi: 10.1038/s41467-023-36148-1

Context-Specific Determinants of the Immunosuppressive Tumor Microenvironment in Pancreatic Cancer


Falcomata, C., Barthel, S., Schneider, G., Rad, R., Schmidt-Supprian, M., and Saur, D. (2023). Cancer Discov 13, 278-297. doi: 10.1158/2159-8290.CD-22-0876