ProjectsProject P01 | Roland RadDissecting cellular and molecular routes to pancreatic cancer phenotypes through genome-wide genetic screening in miceProject P02 | Tatiana Flisikowska, Angelika Schnieke A porcine model of pancreatic ductal adenocarcinomaProject P03 | Roland M. SchmidMolecular determinants of acinar-ductal metaplasia and PanIN lesionsProject P04 | Hana AlgülFunctional characterization of the atypical member of the IkappaB inhibitor Bcl-3 in pancreatic ductal adenocarcinomaProject P05 | Bernhard HolzmannDissecting Toll-like receptor 3 function in pancreatic regeneration and neoplastic transformationProject P06 | Dieter Saur, Marc Schmidt-SupprianDefining and targeting subtype specific inflammatory drivers in pancreatic cancerProject P07 | Ihsan Ekin DemirFunctional characterization of neuropathy and neural invasion (NI) in genetically engineered mouse models (GEMM) of pancreatic ductal adenocarcinoma (PDAC)Project P08 | Kerstin Stemmer, Matthias H. TschöpEffects of obesity and anti-obesity treatments on pancreatic cancerProject P09 | Mauricio Berriel Diaz, Stephan Herzig Identification of tumor-borne mediators of pancreatic cancer-associated cachexiaProject P10 | Bernd Engelmann, Steffen MassbergMechanisms promoting coagulation responses and thrombosis in pancreatic cancer metastasisProject P11 | Maria S. Robles, Dieter Saur Proteomics subtyping and circadian dynamics of PDACs to develop novel therapeutic strategiesProject P12 | Maximilian ReichertTargeting epithelial plasticity in pancreatic cancerProject P13 | Günter Schneider, Gunnar Schotta Development of epigenetic-based therapies for PDACProject P14 | Julia MayerleThe biological role of Sphingolipids in pancreatic cancerProject P15 | Stephanie CombsIdentification of biomarkers to predict individual radiosensitivity using pre-clinical pancreatic cancer models and development of innovative chemo-radiation therapy conceptsProject P16 | Kirsten Lauber, Max Schnurr Radioimmunotherapy of pancreatic cancer: From target validation to treatment responseProject P17 | Markus Gerhard, Dirk H. Busch Neo-epitopes derived from the mutated tumor suppressor gene RNF43 as targets for T cell therapy in pancreatic cancerProject P18 | Bernhard KüsterPrediction of drug sensitivity and resistance of pancreatic cancer cell linesService Project S01 | Roland Rad, Maximilian Reichert, Dieter Saur, Günter Schneider, Katja Steiger, Wilko WeichertExperimental resource and service platformService Project S02 | Klaus A. Kuhn, Roland RadCancer genomics, sequencing, informatics and data integration platform
