Publications of the SFB 1321

Publications



ChipCytometry for multiplexed detection of protein and mRNA markers on human FFPE tissue samples


Jarosch, S., Kohlen, J., Wagner, S., D'Ippolito, E., and Busch, D. H. (2022). STAR Protoc 3, 101374. doi: 10.1016/j.xpro.2022.101374

Suppression of Endothelial Cell FAK Expression Reduces Pancreatic Ductal Adenocarcinoma Metastasis after Gemcitabine Treatment


Roy-Luzarraga, M., Reynolds, L. E., de Luxan-Delgado, B., Maiques, O., Wisniewski, L., Newport, E., Rajeeve, V., Drake, R. J. G., Gomez-Escudero, J., Richards, F. M., Weller, C., Dormann, C., Meng, Y. M., Vermeulen, P. B., Saur, D., Sanz-Moreno, V., Wong, P. P., Geraud, C., Cutillas, P. R., and Hodivala-Dilke, K. (2022). Cancer Res 82, 1909-1925. doi: 10.1158/0008-5472.CAN-20-3807

Single-cell profiling guided combination therapy of c-Fos and histone deacetylase inhibitors in diffuse large B-cell lymphoma


Kramer, O. H., and Schneider, G. (2022). Clin Transl Med 12, e858. doi: 10.1002/ctm2.858

Detecting drug resistance in pancreatic cancer organoids guides optimized chemotherapy treatment


Hennig, A., Baenke, F., Klimova, A., Drukewitz, S., Jahnke, B., Bruckmann, S., Secci, R., Winter, C., Schmache, T., Seidlitz, T., Bereuter, J. P., Polster, H., Eckhardt, L., Schneider, S. A., Bruckner, S., Schmelz, R., Babatz, J., Kahlert, C., Distler, M., Hampe, J., Reichert, M., Zeissig, S., Folprecht, G., Weitz, J., Aust, D., Welsch, T., and Stange, D. E. (2022). J Pathol [Epub ahead of print]. doi: 10.1002/path.5906

Suppression of mutant Kirsten-RAS (KRASG12D)-driven pancreatic carcinogenesis by dual-specificity MAP kinase phosphatases 5 and 6


Kidger, A. M., Saville, M. K., Rushworth, L. K., Davidson, J., Stellzig, J., Ono, M., Kuebelsbeck, L. A., Janssen, K. P., Holzmann, B., Morton, J. P., Sansom, O. J., Caunt, C. J., and Keyse, S. M. (2022). Oncogene 41, 2811-2823. doi: 10.1038/s41388-022-02302-0

Perseus plugin "Metis" for metabolic-pathway-centered quantitative multi-omics data analysis for static and time-series experimental designs


Hamzeiy, H., Ferretti, D., Robles, M. S., and Cox, J. (2022). Cell Rep Methods 2, 100198. doi: 10.1016/j.crmeth.2022.100198

Identification of treatment-induced vulnerabilities in pancreatic cancer patients using functional model systems


Peschke, K., Jakubowsky, H., Schafer, A., Maurer, C., Lange, S., Orben, F., Bernad, R., Harder, F. N., Eiber, M., Ollinger, R., Steiger, K., Schlitter, M., Weichert, W., Mayr, U., Phillip, V., Schlag, C., Schmid, R. M., Braren, R. F., Kong, B., Demir, I. E., Friess, H., Rad, R., Saur, D., Schneider, G., and Reichert, M. (2022). EMBO Mol Med 14, e14876. doi: 10.15252/emmm.202114876

CRISPR somatic genome engineering and cancer modeling in the mouse pancreas and liver


Kaltenbacher, T., Loprich, J., Maresch, R., Weber, J., Muller, S., Oellinger, R., Gross, N., Griger, J., de Andrade Kratzig, N., Avramopoulos, P., Ramanujam, D., Brummer, S., Widholz, S. A., Barthel, S., Falcomata, C., Pfaus, A., Alnatsha, A., Mayerle, J., Schmidt-Supprian, M., Reichert, M., Schneider, G., Ehmer, U., Braun, C. J., Saur, D., Engelhardt, S., and Rad, R. (2022). Nat Protoc 17, 1142-1188. doi: 10.1038/s41596-021-00677-0

Indirect targeting of MYC sensitizes pancreatic cancer cells to mechanistic target of rapamycin (mTOR) inhibition


Schneeweis, C., Hassan, Z., Ascherl, K., Wirth, M., Koutsouli, S., Orben, F., Krauss, L., Schneider, C., Ollinger, R., Kramer, O. H., Rad, R., Reichert, M., Robles, M. S., Saur, D., and Schneider, G. (2022). Cancer Commun (Lond) 42, 360-364. doi: 10.1002/cac2.12280

Global koff -rates of polyclonal T-cell populations merge subclonal avidities and predict functionality


Luckemeier, P., Molter, K. L., Jarosch, S., Huppertz, P., Purcarea, A., Effenberger, M. J. P., Nauerth, M., D'Ippolito, E., Schober, K., and Busch, D. H. (2022). Eur J Immunol 52, 582-596. doi: 10.1002/eji.202149597