Publications



Combination therapies induce cancer cell death through the integrated stress response and disturbed pyrimidine metabolism


Hartleben, G., Schorpp, K., Kwon, Y., Betz, B., Tsokanos, F. F., Dantes, Z., Schafer, A., Rothenaigner, I., Monroy Kuhn, J. M., Morigny, P., Mehr, L., Lin, S., Seitz, S., Tokarz, J., Artati, A., Adamsky, J., Plettenburg, O., Lutter, D., Irmler, M., Beckers, J., Reichert, M., Hadian, K., Zeigerer, A., Herzig, S., and Berriel Diaz, M. (2021). EMBO Mol Med 13, e12461

Chemokines: the (un)usual suspects in pancreatic cancer neural invasion


Demir, I. E., and Mota Reyes, C. (2020). Nat Rev Gastroenterol Hepatol

Toll-like receptor 3 expression in myeloid cells is essential for efficient regeneration after acute pancreatitis in mice


Hidalgo-Sastre, A., Kuebelsbeck, L. A., Jochheim, L. S., Staufer, L. M., Altmayr, F., Johannes, W., Steiger, K., Ronderos, M., Hartmann, D., Huser, N., Schmid, R. M., Holzmann, B., and von Figura, G. (2021). Eur J Immunol [Epub ahead of print].

Allelic Expression Imbalance Analysis Identified YAP1 Amplification in p53- Dependent Osteosarcoma


Niu, G., Bak, A., Nusselt, M., Zhang, Y., Pausch, H., Flisikowska, T., Schnieke, A. E., and Flisikowski, K. (2021). Cancers (Basel) 13

Robust Microflow LC-MS/MS for Proteome Analysis: 38 000 Runs and Counting


Bian, Y. Y., Bayer, F. P., Chang, Y. C., Meng, C., Hoefer, S., Deng, N., Zheng, R. S., Boychenko, O., and Kuster, B. (2021). Anal Chem 93, 3686-3690

Effects of COVID-19 Pandemic on the Treatment of Pancreatic Cancer: A Perspective from Central Europe


Pergolini, I., Demir, I. E., Stoss, C., Emmanuel, K., Rosenberg, R., Friess, H., and Novotny, A. (2021). Dig Surg 38, 158-165

Aggressive PDACs Show Hypomethylation of Repetitive Elements and the Execution of an Intrinsic IFN Program Linked to a Ductal Cell of Origin


Espinet, E., Gu, Z., Imbusch, C. D., Giese, N. A., Buscher, M., Safavi, M., Weisenburger, S., Klein, C., Vogel, V., Falcone, M., Insua-Rodriguez, J., Reitberger, M., Thiel, V., Kossi, S. O., Muckenhuber, A., Sarai, K., Lee, A. Y. L., Backx, E., Zarei, S., Gaida, M. M., Rodriguez-Paredes, M., Donato, E., Yen, H. Y., Eils, R., Schlesner, M., Pfarr, N., Hackert, T., Plass, C., Brors, B., Steiger, K., Weichenhan, D., Arda, H. E., Rooman, I., Kopp, J. L., Strobel, O., Weichert, W., Sprick, M. R., and Trumpp, A. (2021). Cancer Discov 11, 638-659

Identification and validation of a multivariable prediction model based on blood plasma and serum metabolomics for the distinction of chronic pancreatitis subjects from non-pancreas disease control subjects


Adam, M. G., Beyer, G., Christiansen, N., Kamlage, B., Pilarsky, C., Distler, M., Fahlbusch, T., Chromik, A., Klein, F., Bahra, M., Uhl, W., Grutzmann, R., Mahajan, U. M., Weiss, F. U., Mayerle, J., and Lerch, M. M. (2021). Gut [Epub ahead of print]

SETDB1 is required for intestinal epithelial differentiation and the prevention of intestinal inflammation


Juznic, L., Peuker, K., Strigli, A., Brosch, M., Herrmann, A., Hasler, R., Koch, M., Matthiesen, L., Zeissig, Y., Loscher, B. S., Nuber, A., Schotta, G., Neumeister, V., Chavakis, T., Kurth, T., Lesche, M., Dahl, A., von Massenhausen, A., Linkermann, A., Schreiber, S., Aden, K., Rosenstiel, P. C., Franke, A., Hampe, J., and Zeissig, S. (2021). Gut 70, 485-498

Porcine model elucidates function of p53 isoform in carcinogenesis and reveals novel circTP53 RNA


Niu, G., Hellmuth, I., Flisikowska, T., Pausch, H., Rieblinger, B., Carrapeiro, A., Schade, B., Bohm, B., Kappe, E., Fischer, K., Klinger, B., Steiger, K., Burgkart, R., Bourdon, J. C., Saur, D., Kind, A., Schnieke, A., and Flisikowski, K. (2021). Oncogene 40, 1896-1908