Publications of the SFB 1321

Publications



Activated regulatory T-cells promote duodenal bacterial translocation into necrotic areas in severe acute pancreatitis


Glaubitz, J., Wilden, A., Frost, F., Ameling, S., Homuth, G., Mazloum, H., Ruhlemann, M. C., Bang, C., Aghdassi, A. A., Budde, C., Pickartz, T., Franke, A., Broker, B. M., Voelker, U., Mayerle, J., Lerch, M. M., Weiss, F. U., and Sendler, M. (2023). Gut 72, 1355-1369. doi: 10.1136/gutjnl-2022-327448

Resistance to mesenchymal reprogramming sustains clonal propagation in metastatic breast cancer


Saini, M., Schmidleitner, L., Moreno, H. D., Donato, E., Falcone, M., Bartsch, J. M., Klein, C., Vogel, V., Wurth, R., Pfarr, N., Espinet, E., Lehmann, M., Konigshoff, M., Reitberger, M., Haas, S., Graf, E., Schwarzmayr, T., Strom, T. M., Spaich, S., Sutterlin, M., Schneeweiss, A., Weichert, W., Schotta, G., Reichert, M., Aceto, N., Sprick, M. R., Trumpp, A., and Scheel, C. H. (2023). Cell Rep, 112533 [Epub ahead of print]. doi: 10.1016/j.celrep.2023.112533

Consensus definition of sludge and microlithiasis as a possible cause of pancreatitis


Zorniak, M., Sirtl, S., Beyer, G., Mahajan, U. M., Bretthauer, K., Schirra, J., Schulz, C., Kohlmann, T., Lerch, M. M., Mayerle, J., and Team, L. M. E. S. (2023). Gut [Epub ahead of print]. doi: 10.1136/gutjnl-2022-327955

Cell-selective proteomics segregates pancreatic cancer subtypes by extracellular proteins in tumors and circulation


Swietlik, J. J., Barthel, S., Falcomata, C., Fink, D., Sinha, A., Cheng, J., Ebner, S., Landgraf, P., Dieterich, D. C., Daub, H., Saur, D., and Meissner, F. (2023). Nat Commun 14, 2642. doi: 10.1038/s41467-023-38171-8

Accurate prediction of histological grading of intraductal papillary mucinous neoplasia using deep learning


Schulz, D., Heilmaier, M., Phillip, V., Treiber, M., Mayr, U., Lahmer, T., Mueller, J., Demir, I. E., Friess, H., Reichert, M., Schmid, R. M., and Abdelhafez, M. (2023). Endoscopy 55, 415-422. doi: 10.1055/a-1971-1274

Single-cell profiling to explore pancreatic cancer heterogeneity, plasticity and response to therapy


Barthel, S., Falcomata, C., Rad, R., Theis, F. J., and Saur, D. (2023). Nat Cancer 4, 454-467. doi: 10.1038/s43018-023-00526-x

In vivo interrogation of regulatory genomes reveals extensive quasi-insufficiency in cancer evolution


Fischer, A., Lersch, R., de Andrade Kratzig, N., Strong, A., Friedrich, M. J., Weber, J., Engleitner, T., Ollinger, R., Yen, H. Y., Kohlhofer, U., Gonzalez-Menendez, I., Sailer, D., Kogan, L., Lahnalampi, M., Laukkanen, S., Kaltenbacher, T., Klement, C., Rezaei, M., Ammon, T., Montero, J. J., Schneider, G., Mayerle, J., Heikenwalder, M., Schmidt-Supprian, M., Quintanilla-Martinez, L., Steiger, K., Liu, P., Cadinanos, J., Vassiliou, G. S., Saur, D., Lohi, O., Heinaniemi, M., Conte, N., Bradley, A., Rad, L., and Rad, R. (2023). Cell Genom 3, 100276. doi: 10.1016/j.xgen.2023.100276

Long-term persistence and functionality of adoptively transferred antigen-specific T cells with genetically ablated PD-1 expression


Dotsch, S., Svec, M., Schober, K., Hammel, M., Wanisch, A., Gokmen, F., Jarosch, S., Warmuth, L., Barton, J., Cicin-Sain, L., D'Ippolito, E., and Busch, D. H. (2023). Proc Natl Acad Sci U S A 120, e2200626120. doi: 10.1073/pnas.2200626120

Non-canonical functions of SNAIL drive context-specific cancer progression


Paul, M. C., Schneeweis, C., Falcomata, C., Shan, C., Rossmeisl, D., Koutsouli, S., Klement, C., Zukowska, M., Widholz, S. A., Jesinghaus, M., Heuermann, K. K., Engleitner, T., Seidler, B., Sleiman, K., Steiger, K., Tschurtschenthaler, M., Walter, B., Weidemann, S. A., Pietsch, R., Schnieke, A., Schmid, R. M., Robles, M. S., Andrieux, G., Boerries, M., Rad, R., Schneider, G., and Saur, D. (2023). Nat Commun 14, 1201. doi: 10.1038/s41467-023-36505-0

Definition of age-dependent reference values for the diameter of the common bile duct and pancreatic duct on MRCP: a population-based, cross-sectional cohort study


Beyer, G., Kasprowicz, F., Hannemann, A., Aghdassi, A., Thamm, P., Volzke, H., Lerch, M. M., Kuhn, J. P., and Mayerle, J. (2023). Gut [Epub ahead of print]. doi: 10.1136/gutjnl-2021-326106