Publications of the SFB 1321

Publications



Toll-like receptor 3 expression in myeloid cells is essential for efficient regeneration after acute pancreatitis in mice


Hidalgo-Sastre, A., Kuebelsbeck, L. A., Jochheim, L. S., Staufer, L. M., Altmayr, F., Johannes, W., Steiger, K., Ronderos, M., Hartmann, D., Huser, N., Schmid, R. M., Holzmann, B., and von Figura, G. (2021). Eur J Immunol 51, 1182-1194. doi: 10.1002/eji.202048771

Combination therapies induce cancer cell death through the integrated stress response and disturbed pyrimidine metabolism


Hartleben, G., Schorpp, K., Kwon, Y., Betz, B., Tsokanos, F. F., Dantes, Z., Schafer, A., Rothenaigner, I., Monroy Kuhn, J. M., Morigny, P., Mehr, L., Lin, S., Seitz, S., Tokarz, J., Artati, A., Adamsky, J., Plettenburg, O., Lutter, D., Irmler, M., Beckers, J., Reichert, M., Hadian, K., Zeigerer, A., Herzig, S., and Berriel Diaz, M. (2021). EMBO Mol Med 13, e12461. doi: 10.15252/emmm.202012461

Epstein-Barr virus inactivates the transcriptome and disrupts the chromatin architecture of its host cell in the first phase of lytic reactivation


Buschle, A., Mrozek-Gorska, P., Cernilogar, F. M., Ettinger, A., Pich, D., Krebs, S., Mocanu, B., Blum, H., Schotta, G., Straub, T., and Hammerschmidt, W. (2021). Nucleic Acids Res 49, 3217-3241. doi: 10.1093/nar/gkab099

Important role of Nfkb2 in the Kras(G12D)-driven carcinogenesis in the pancreas


Hassan, Z., Schneeweis, C., Wirth, M., Muller, S., Geismann, C., Neuss, T., Steiger, K., Kramer, O. H., Schmid, R. M., Rad, R., Arlt, A., Reichert, M., Saur, D., and Schneider, G. (2021). Pancreatology 21(5):912-919. doi: 10.1016/j.pan.2021.03.012

PALLD mutation in a European family conveys a stromal predisposition for familial pancreatic cancer


Liotta, L., Lange, S., Maurer, H. C., Olive, K. P., Braren, R., Pfarr, N., Muckenhuber, A., Jesinghaus, M., Weichert, W., Steiger, K., Burger, S., Friess, H., Schmid, R. M., Alguel, H., Jost, P., Ramser, J., Fischer, C., Quante, A. S., Reichert, M., and Quante, M. (2021). JCI Insight 6. doi: 10.1172/jci.insight.141532

Allelic Expression Imbalance Analysis Identified YAP1 Amplification in p53- Dependent Osteosarcoma


Niu, G., Bak, A., Nusselt, M., Zhang, Y., Pausch, H., Flisikowska, T., Schnieke, A. E., and Flisikowski, K. (2021). Cancers (Basel) 13. doi: 10.3390/cancers13061364

Robust Microflow LC-MS/MS for Proteome Analysis: 38 000 Runs and Counting


Bian, Y. Y., Bayer, F. P., Chang, Y. C., Meng, C., Hoefer, S., Deng, N., Zheng, R. S., Boychenko, O., and Kuster, B. (2021). Anal Chem 93, 3686-3690. doi: 10.1021/acs.analchem.1c00257

Effects of COVID-19 Pandemic on the Treatment of Pancreatic Cancer: A Perspective from Central Europe


Pergolini, I., Demir, I. E., Stoss, C., Emmanuel, K., Rosenberg, R., Friess, H., and Novotny, A. (2021). Dig Surg 38, 158-165. doi: 10.1159/000513157

Aggressive PDACs Show Hypomethylation of Repetitive Elements and the Execution of an Intrinsic IFN Program Linked to a Ductal Cell of Origin


Espinet, E., Gu, Z., Imbusch, C. D., Giese, N. A., Buscher, M., Safavi, M., Weisenburger, S., Klein, C., Vogel, V., Falcone, M., Insua-Rodriguez, J., Reitberger, M., Thiel, V., Kossi, S. O., Muckenhuber, A., Sarai, K., Lee, A. Y. L., Backx, E., Zarei, S., Gaida, M. M., Rodriguez-Paredes, M., Donato, E., Yen, H. Y., Eils, R., Schlesner, M., Pfarr, N., Hackert, T., Plass, C., Brors, B., Steiger, K., Weichenhan, D., Arda, H. E., Rooman, I., Kopp, J. L., Strobel, O., Weichert, W., Sprick, M. R., and Trumpp, A. (2021). Cancer Discov 11, 638-659. doi: 10.1158/2159-8290.CD-20-1202

SETDB1 is required for intestinal epithelial differentiation and the prevention of intestinal inflammation


Juznic, L., Peuker, K., Strigli, A., Brosch, M., Herrmann, A., Hasler, R., Koch, M., Matthiesen, L., Zeissig, Y., Loscher, B. S., Nuber, A., Schotta, G., Neumeister, V., Chavakis, T., Kurth, T., Lesche, M., Dahl, A., von Massenhausen, A., Linkermann, A., Schreiber, S., Aden, K., Rosenstiel, P. C., Franke, A., Hampe, J., and Zeissig, S. (2021). Gut 70, 485-498. doi: 10.1136/gutjnl-2020-321339