Publications of the SFB 1321

Publications



OAS1/RNase L executes RIG-I ligand-dependent tumor cell apoptosis


Boehmer, D. F. R., Formisano, S., de Oliveira Mann, C. C., Mueller, S. A., Kluge, M., Metzger, P., Rohlfs, M., Horth, C., Kocheise, L., Lichtenthaler, S. F., Hopfner, K. P., Endres, S., Rothenfusser, S., Friedel, C. C., Duewell, P., Schnurr, M., and Koenig, L. M. (2021). Sci Immunol 6. doi: 10.1126/sciimmunol.abe2550

Plasma Metabolome Profiling Identifies Metabolic Subtypes of Pancreatic Ductal Adenocarcinoma


Mahajan, U. M., Alnatsha, A., Li, Q., Oehrle, B., Weiss, F. U., Sendler, M., Distler, M., Uhl, W., Fahlbusch, T., Goni, E., Beyer, G., Chromik, A., Bahra, M., Klein, F., Pilarsky, C., Grutzmann, R., Lerch, M. M., Lauber, K., Christiansen, N., Kamlage, B., Regel, I., and Mayerle, J. (2021). Cells 10. doi: 10.3390/cells10071821

Bcl3 Couples Cancer Stem Cell Enrichment With Pancreatic Cancer Molecular Subtypes


Ai, J., Wormann, S. M., Gorgulu, K., Vallespinos, M., Zagorac, S., Alcala, S., Wu, N., Kabacaoglu, D., Berninger, A., Navarro, D., Kaya-Aksoy, E., Ruess, D. A., Ciecielski, K. J., Kowalska, M., Demir, I. E., Ceyhan, G. O., Heid, I., Braren, R., Riemann, M., Schreiner, S., Hofmann, S., Kutschke, M., Jastroch, M., Slotta-Huspenina, J., Muckenhuber, A., Schlitter, A. M., Schmid, R. M., Steiger, K., Diakopoulos, K. N., Lesina, M., Sainz, B., Jr., and Algul, H. (2021). Gastroenterology 161, 318-332 e319. doi: 10.1053/j.gastro.2021.03.051

Promoter G-quadruplexes and transcription factors cooperate to shape the cell type-specific transcriptome


Lago, S., Nadai, M., Cernilogar, F. M., Kazerani, M., Dominiguez Moreno, H., Schotta, G., and Richter, S. N. (2021). Nat Commun 12, 3885. doi: 10.1038/s41467-021-24198-2

Modeling plasticity and dysplasia of pancreatic ductal organoids derived from human pluripotent stem cells


Breunig, M., Merkle, J., Wagner, M., Melzer, M. K., Barth, T. F. E., Engleitner, T., Krumm, J., Wiedenmann, S., Cohrs, C. M., Perkhofer, L., Jain, G., Kruger, J., Hermann, P. C., Schmid, M., Madacsy, T., Varga, A., Griger, J., Azoitei, N., Muller, M., Wessely, O., Robey, P. G., Heller, S., Dantes, Z., Reichert, M., Gunes, C., Bolenz, C., Kuhn, F., Maleth, J., Speier, S., Liebau, S., Sipos, B., Kuster, B., Seufferlein, T., Rad, R., Meier, M., Hohwieler, M., and Kleger, A. (2021). Cell Stem Cell 28, 1105-1124 e1119. doi: 10.1016/j.stem.2021.03.005

Disorders of the enteric nervous system - a holistic view


Niesler, B., Kuerten, S., Demir, I. E., and Schafer, K. H. (2021). Nat Rev Gastroenterol Hepatol 18, 393-410. doi: 10.1038/s41575-020-00385-2

Impact of DNA repair and reactive oxygen species levels on radioresistance in pancreatic cancer


Nguyen, L., Dobiasch, S., Schneider, G., Schmid, R. M., Azimzadeh, O., Kanev, K., Buschmann, D., Pfaffl, M. W., Bartzsch, S., Schmid, T. E., Schilling, D., and Combs, S. E. (2021). Radiother Oncol 159, 265-276. doi: 10.1016/j.radonc.2021.03.038

Defective Interfering Genomes and the Full-Length Viral Genome Trigger RIG-I After Infection With Vesicular Stomatitis Virus in a Replication Dependent Manner


Linder, A., Bothe, V., Linder, N., Schwarzlmueller, P., Dahlstrom, F., Bartenhagen, C., Dugas, M., Pandey, D., Thorn-Seshold, J., Boehmer, D. F. R., Koenig, L. M., Kobold, S., Schnurr, M., Raedler, J., Spielmann, G., Karimzadeh, H., Schmidt, A., Endres, S., and Rothenfusser, S. (2021). Front Immunol 12, 595390. doi: 10.3389/fimmu.2021.595390

Toll-like receptor 3 expression in myeloid cells is essential for efficient regeneration after acute pancreatitis in mice


Hidalgo-Sastre, A., Kuebelsbeck, L. A., Jochheim, L. S., Staufer, L. M., Altmayr, F., Johannes, W., Steiger, K., Ronderos, M., Hartmann, D., Huser, N., Schmid, R. M., Holzmann, B., and von Figura, G. (2021). Eur J Immunol 51, 1182-1194. doi: 10.1002/eji.202048771

Combination therapies induce cancer cell death through the integrated stress response and disturbed pyrimidine metabolism


Hartleben, G., Schorpp, K., Kwon, Y., Betz, B., Tsokanos, F. F., Dantes, Z., Schafer, A., Rothenaigner, I., Monroy Kuhn, J. M., Morigny, P., Mehr, L., Lin, S., Seitz, S., Tokarz, J., Artati, A., Adamsky, J., Plettenburg, O., Lutter, D., Irmler, M., Beckers, J., Reichert, M., Hadian, K., Zeigerer, A., Herzig, S., and Berriel Diaz, M. (2021). EMBO Mol Med 13, e12461. doi: 10.15252/emmm.202012461