Teaching
The CRC is committed to foster interdisciplinary training of our PhD/MD students. We implemented specific lectures and courses in the TUM Medical Life Science and Technology Program tailored to the doctoral researchers of the CRC.
Modelling and Targeting Pancreatic Cancer
In this lecture program we will present the state of the art knowledge of pancreatic cancer research. Top representatives of the respective research fields will give an overview of implications of their field of research with respect to pancreatic cancer pathogenesis, diagnosis, and treatment.
Module I and Module II take place alternately.
The lecture series is part of the PhD program "Medical life science and technology" of the TUM Graduate School(link is external).
Anyone who is interested is very welcome!
Venue:
Online via Zoom.
If you are interested, please contact the office of the SFB for dial-in details:
Email: sfb1321@mri.tum.de(link sends e-mail)
Phone: +49.89.4140.4797
Module II
18.10.2022 Generating and investigating large animal models of PDAC (T. Flisikowska, Project P02)
25.10.2022 Metabolic vulnerabilities of GI cancers (D. Wolf)
08.11.2022 Irradiation of PDAC: From the clinical to mechanistic insights (S. Dobiasch, Project P15)
15.11.2022 Personalized treatment of PDAC (R. M. Schmid)
22.11.2022 Therapeutic Targeting of PDAC (G. Schneider, Project P13)
29.11.2022 Lipid metabolism and PDAC: From mechanisms to biomarkers (U. Mahajan, Project P14)
06.12.2022 Murine models of PDAC (D. Saur, Project P06)
13.12.2022 Analysis of clonogenic growth in vitro: 2D and complex cell culture models, upscaling, and mathematical analysis algorithms (K. Lauber, Project P16)
10.01.2023 High-throughput drug screens in pancreatic cancer (C. Schneeweis, Service Project S01)
24.01.2023 Organoid platform (M. Reichert, Service Project S01)
31.01.2023 RNF43 as a potential immunotherapeutic target in GI cancers (M. Gerhard, Project P17)
07.02.2023 High-dimensional genetic screening to interrogate coding and regulatory genomes (R. Rad, Service Project S02)
21.02.2023 Adding a proteomic component to molecular tumor boards (B. Küster, Project P18)
Module I
Plasticity in PDAC initiation and progression (Project P12)
Clinic of PDAC for scientists (Project P03)
Genetics of PDAC (Project P01)
Mouse models to dissect immunopathways in PDAC (Project P06)
Role of inflammatory signalling pathways in PDAC (Project P04)
Role of the nerve system in PDAC biology (Project P07)
Diabetes and PDAC cachexia – Molecular mechanisms and therapeutic consequences (Project P09)
Microfluidic based in vitro systems for modeling pancreatic cancer (Matthias Meier/Helmholtz Zentrum München)
Dissecting the Role of APOBEC3A in driving drug resistance in PDAC (Sonja Wörmann/TUM)
Phospholipid composition of pancreatic cancer as therapeutic target in coagulopathy and metastasis (Konstantin Stark/LMU)
Disrupting spliceosome-licensed oncogene collaboration networks for precision cancer therapy (Christian Braun/LMU)
Technics to understand Epigenetic Aspects of PDAC (Project P13)
PDAC Pathology (Service Project S01)
- Translational Cancer Research
Next course date: tbaModule 1: Organoids, spheroids and 2D cell culture
Module 2: Advanced mouse models of cancer
Module 3: Reporter systems: Ex vivo and in vitro imaging.
Module 4: High throughput drug/genetic screening and barcoding systems. - Organoids and beyond
Next course date: tba
Organoids are three dimensional (3D) ex-vivo culture systems derived from self-organizing stem cells. Organoids represent a very versatile in vitro model system that allows genetic manipulation (e.g. by CRISPR/Cas9 technology), discovery and validation of preclinical drugs, testing of drug sensitivity and assessment of responsiveness to drug combinations. Organoids have therefore emerged as an invaluable tool for research that enables to improve our current understanding of stem cell biology, organogenesis, and various human diseases, including cancer. Content of this workshop is to gain theoretical and practical experience in generating 3D organoids and other cellular models systems such as cancer-associated fibroblasts.
The lab courses are part of the PhD program "Medical life science and technology" of the TUM Graduate School(link is external).
For further information and registration, please contact mgc.med@tum.de(link sends e-mail)
maximilian.reichert@tum.de(link sends e-mail)
Homepage(link is external)